
MOTS-c
MOTS-c (Mitochondrial ORF of the 12S rRNA type-c)
MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within the 12S rRNA gene. It is one of the principal reference peptides in research on mitochondrial-nuclear signalling, and is widely used in metabolic cell-culture studies examining AMPK activation and folate-cycle interactions.
Supplied as: White to off-white lyophilised powder in a sealed, batch-labelled vial. ≥99% by RP-HPLC with diode-array detection; identity confirmed by mass spectrometry.
Research use only. This material is supplied for laboratory research purposes. Not for human or veterinary consumption, not a medicine, and not for diagnostic or therapeutic use.
Product information
Identity & specification
| Compound | MOTS-c (Mitochondrial ORF of the 12S rRNA type-c) |
|---|---|
| Sequence | MRWQEMGYIFYPRKLR |
| Full sequence | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg |
| Molecular formula | C101H152N28O22S2 |
| Molecular weight | 2174.55 g/mol |
| CAS number | 1627580-64-6 |
| Chain length | 16 amino acids |
| Appearance | White to off-white lyophilised peptide (vial) or pre-made solution (pen), sealed and batch-labelled |
| Purity | ≥99% by RP-HPLC with diode-array detection; identity confirmed by mass spectrometry |
| Solubility | Soluble in sterile water; gentle swirling recommended |
| Research area | Mitochondrial-derived peptide and AMPK pathway research |
Values above are reference figures for the compound. The certificate of analysis for your batch is the authority — it carries the measured purity and the batch code printed on the label.
Research information
MOTS-c (Mitochondrial ORF of the 12S rRNA type-c)
MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within the 12S rRNA gene. It is one of the principal reference peptides in research on mitochondrial-nuclear signalling, and is widely used in metabolic cell-culture studies examining AMPK activation and folate-cycle interactions.
Supplied as: White to off-white lyophilised powder in a sealed, batch-labelled vial. ≥99% by RP-HPLC with diode-array detection; identity confirmed by mass spectrometry.
Research use only. This material is supplied for laboratory research purposes. Not for human or veterinary consumption, not a medicine, and not for diagnostic or therapeutic use.
Handling & reconstitution
Allow the material to reach room temperature before opening. Lyophilised material must be reconstituted with an appropriate sterile diluent — run the diluent slowly down the inside wall and swirl gently to dissolve; do not shake or vortex, as peptides are shear-sensitive. Pre-made solution requires no reconstitution. Keep opened or reconstituted material refrigerated and use within the working window established for your assay.
Handling, reconstitution and disposal are the recipient's responsibility and must follow your own laboratory protocols. Reconstitution calculator.
Storage & stability
Documentation
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Important information
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